Enantioselective acylation of silyl ketene acetals through fluoride anion-binding catalysis.
نویسندگان
چکیده
A highly enantioselective acylation of silyl ketene acetals with acyl fluorides has been developed to generate useful α,α-disubstituted butyrolactone products. This transformation is promoted by a new thiourea catalyst and 4-pyrrolidinopyridine and represents the first example of enantioselective thiourea anion-binding catalysis with fluoride.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 133 35 شماره
صفحات -
تاریخ انتشار 2011